EXPRESSION OF GLUCOSE TRANSPORTERS ON PLACENTAL VILI THROUGH GESTATION

N.V. Aleksandrova, E.A. Dubova, O.R. Baev, A.I. Shchegolev, G.T. Sukhikh
Federal State Budget Institution «Research Center for Obstetrics, Gynecology and Perinatology» of the Ministry of Healthcare and Social Development of the Russian Federation

Immunohystochemical examination revealed increasing of GLUT1 and decreasing of GLUT3 expression through gestation. In cases with missed abortion higher expression of GLUT1 and lower expression of GLUT3 in comparison with their expression in control group are characteristic that may indicate abnormal estation. Revealed differences in GLUT expression in cases with spontaneous pregnancy and pregnancy after assisted reproduction technologies may be associated with the various rate of obstetrics complications.
Keywords: 
placental vili, missed abortion, immunohistochemistry, glucose transporters (GLUT1 и GLUT3)