GENETIC ASPECTS OF ARTERIAL HYPERTENSION IN CHILDREN

G.I. Obraztsova (1), V.V. Yurev (2), A.S. Glotov (2), T.E. Ivashchenko (2)
1 -Almazov Federal Heart, Blood and Endocrinology Centre, of the Russian Academy of Medical Sciences,
Russia, St. Petersburg; 2 -Scientific Research Institute of Obstetrics and Gynecology named after D.O. Ott of the Russian Academy of Medical Sciences, Russia, St. Petersburg

The article presents results of a comparison of clinical, genealogical and molecular genetic data of the study of the role of gene polymorphisms of renin - angiotensin system (REN (G83A), AGT (M235T), AGTR1 (A1166C)) in children with hypertension, with taking into account the results of ambulatory blood pressure monitoring. This study is representing a considerable contribution of genetic factors in the development and progression of hypertension in children. The obtained results can be used to develop primary prevention of hypertension in children.
Keywords: 
hypertension, genetic markers, metabolic syndrome, children